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Table 4 Genotype frequency of the i-T744C SNP of the P2RY12 gene according to smoking habit

From: Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

  Smokers (n = 809) Non-smokers (n = 503)
  CAD CAD-free OR (CI 95%) p-value * CAD CAD-free OR (CI 95%) p-value *
T/T 490 (75.4%) 121 (76.1%)   221 (72.5%) 164 (82.8%)  
T/C 150 (23%) 35 (22%) 1.04
(0.69–1.56)
81 (26.5%) 28 (14.2%) 1.83
C/C 10 (1.6%) 3 (1.9%) p = 0.85 3 (1%) 6 (3%) (1.17–2.87)
TC+CC 160 (24.6%) 38 (23.9%)   84 (27.5%) 34 (17.2%) p = 0.007
  1. *T/C and C/C genotypes (H1/H2 and H2/H2 haplotypes, respectively) are pooled in the CAD and in the CAD-free group for p-value and OR calculation.