Table 3 Frequencies of LPL SNPs according to form of dyslipidemia

APOE2/2 patients

ApoB (g/L)/TC (mmol/L) > 0.15

12

12

0

0

-

ApoB (g/L)/TC (mmol/L) < 0.15

88

85

3

0

0.015

Lipid clinic patients

Hypertriglyceridemia (TC ≤ 200 mg/dl, TG > 150 mg/dl) n

89

82

7

0

0.039

Mixed hyperlipidemia (TC > 200 mg/dl, TG > 150 mg/dl) n

601

575

25

1

0.022

Familial defective ApoB (R3500Q carrier) n

52

50

2

0

0.019

Familial hypercholesterolemia (LDL > 330 mg/dl) n

41

38

3

0

0.036

Hypercholesterolemia (TC > 200 mg/dl, TG ≤ 150 mg/dl)

434

420

14

0

0.016

Normal (TC ≤ 200 mg/dl, TG ≤ 150 mg/dl) n

91

87

4

0

0.022

Blood Donors

200

188

12

0

0.03

N291S

n

NN

NS

SS

S Freq

APOE2/2 patients

ApoB (g/L)/TC (mmol/L) > 0.15

12

11

1

0

0.041

ApoB (g/L)/TC (mmol/L) < 0.15

88

83

5

0

0.026

Lipid clinic patients

Hypertriglyceridemia (TC ≤ 200 mg/dl, TG > 150 mg/dl) n

89

78

9

2

0.073

Mixed hyperlipidemia (TC > 200 mg/dl, TG > 150 mg/dl) n

601

560

39

2

0.036

Familial defective ApoB (R3500Q carrier) n

52

49

3

0

0.029

Familial hypercholesterolemia (LDL > 330 mg/dl) n

41

40

1

0

0.012

Hypercholesterolemia (TC > 200 mg/dl, TG ≤ 150 mg/dl)

434

421

13

0

0.015

Normal (TC ≤ 200 mg/dl, TG ≤ 150 mg/dl) n

91

86

5

0

0.027

Blood Donors

200

193

7

0

0.018

S447X

n

SS

SX

XX

X Freq

APOE2/2 patients

ApoB (g/L)/TC (mmol/L) > 0.15

12

12

0

0

-

ApoB (g/L)/TC (mmol/L) < 0.15

88

71

16

1

0.092

Lipid clinic patients

Hypertriglyceridemia (TC ≤ 200 mg/dl, TG > 150 mg/dl) n

89

84

5

0

0.028

Mixed hyperlipidemia (TC > 200 mg/dl, TG > 150 mg/dl) n

601

543

56

2

0.05

Familial defective ApoB (R3500Q carrier) n

52

43

9

0

0.087

Familial hypercholesterolemia (LDL > 330 mg/dl) n

41

34

6

1

0.096

Hypercholesterolemia (TC > 200 mg/dl, TG ≤ 150 mg/dl)

434

357

69

8

0.098

Normal (TC ≤ 200 mg/dl, TG ≤ 150 mg/dl) n

91

80

10

1

0.066

Blood Donors

200

166

34

0

0.085