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Table 3 Analysis of PPAR alpha (L162V) in larger Caucasian only MRI cohort:

From: PPARα L162V underlies variation in serum triglycerides and subcutaneous fat volume in young males

Subcutaneous fat measure Gender SNP N: adjusted mean ± SEM P-value for significantly different means Variability attributable to genotype Likelihood-ratio test p-value *
Full model – with age only adjustment
Trained arm – baseline fat volume Male PPAR alpha (L162V) CC (N = 179; 167221 ± 6710)*
CG (N = 24; 207418 ± 18325) *
* p = 0.041 2.0% 0.039
Trained arm – post-exercise fat volume Male PPAR alpha (L162V) CC (N = 179; 170608 ± 6952)*
CG (N = 24; 214926 ± 18932) *
*p = 0.029 2.3% 0.028
Untrained arm – baseline fat volume Male PPAR alpha (L162V) CC (N = 179; 169890 ± 7106)*
CG (N = 24; 224144 ± 19407) *
*p = 0.033 2.2% 0.031
Untrained arm – post-exercise fat volume Male PPAR alpha (L162V) CC (N = 179; 168183 ± 7241)*
CG (N = 24; 231960 ± 19776) *
*p = 0.003 4.2% 0.003
Untrained arm – difference in fat volume Male PPAR alpha (L162V) CC (N = 179; -1707 ± 2133)*
CG (N = 24; 17617 ± 5826) *
*p = 0.002 4.6% 0.002
Full model – with age and weight adjustment
Untrained arm – difference in fat volume Male PPAR alpha (L162V) CC (N = 179; -1921 ± 2134)*
CG (N = 24; 17612 ± 5825) *
*p = 0.002 4.9% 0.001