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Table 1 Transmission disequilibrium tests of the SNPs in the INS, PTPN22, and CTLA4 gene in the T1D trio set used in this study

From: The TCF7L2locus and type 1 diabetes

gene dbSNP ID minor allele (frequency) Transmission ratio* χ2 (p value) OR (95% CI)
INS rs689 T (0.207) 186:387 70.5 (4.58 × 10-17) 0.48 (0.40, 0.57)
PTPN22 rs2476601 A (0.126) 251:123 43.8 (3.62 × 10-11) 2.04 (1.64, 2.53)
CTLA4 rs231775 G (0.387) 443:382 4.5 (0.034) 1.16 (1.01, 1.33)
CTLA4 rs5742909 T (0.090) 137:178 5.3 (0.021) 0.77 (0.62, 0.96)
  1. * Minor allele transmitted : untransmitted.