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Table 3 Distribution of genotypes and allele frequencies at the APOE gene in the Caucasian cases and controls

From: Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes

Locus

Genotype

Freq(q)

Cases vs. Controls (p-value)

 

AA

Aa

aa

 

Allele

Genotype

SNP1

70

32

1

0.165

0.056

0.142

 

107

71

7

0.230

  

SNP2

102

4

0

0.019

0.371

0.641

 

184

11

1

0.033

  

SNP3

23

53

25

0.490

0.518

0.738

 

41

93

55

0.463

  

SNP4

95

7

0

0.034

0.062

0.144

 

162

22

3

0.075

  

SNP5

55

41

5

0.252

0.570

0.589

 

91

66

14

0.275

  

SNP6

74

27

2

0.150

0.164

0.327

 

124

69

4

0.195

  

SNP7

81

19

0

0.095

0.536

0.503

 

145

35

3

0.112

  

SNP8

45

50

10

0.333

0.304

0.548

 

75

95

26

0.375

  

SNP9

104

1

0

0.005

0.289

0.760

 

185

3

1

0.013

  

SNP10

71

21

2

0.133

0.361

0.675

 

130

48

6

0.163

  

SNP11

105

0

0

-

0.145

0.145

 

194

5

0

0.013

  

SNP12

83

11

0

0.059

0.108

0.213

 

149

34

1

0.098

  

Global

    

0.452

0.807

  1. Note: In Tables 3 and 6, Genotype 'aa' represents the minor homozygous genotype; the first row corresponding to each SNP marker presents the data on cases and the second row presents the data on controls.