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Table 3 Sequence diversity parameters of human PNMT gene region

From: Resequencing PNMTin European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1

    Estonians d Czech d
  kb   Hyper Normo All Hyper Normo All
Sequenced area 3.187 πa 0.00035 0.00039 0.00037 0.0030 0.00024 0.00027
   θb 0.00035 0.00042 0.00036 0.00042 0.00035 0.00036
   Dc 0.01342 -0.16433 0.04368 -0.72287 -0.75219 -0.56268
Gene 2.222 π 0.00026 0.00031 0.00028 0.00032 0.00029 0.00031
   θ 0.00020 0.00040 0.00035 0.00040 0.00030 0.00035
   D 0.51545 -0.52876 -0.37972 -0.48106 -0.05656 -0.24179
Exons 1.157 π 0.00050 0.00056 0.00052 0.00054 0.00050 0.00052
   θ 0.00039 0.00058 0.00050 0.00058 0.00039 0.00050
   D 0.51545 -0.07671 0.07805 -0.13715 0.50566 0.06616
Introns 1.065 π NA 0.00004 0.00002 0.00007 0.00007 0.00007
   θ NA 0.00021 0.00018 0.00021 0.00021 0.00018
   D NA -1.10280 -1.02786 -0.87191 -0.87191 -0.68607
5'upstream region 0.882 π 0.00114 0.00120 0.00116 0.00138 0.00099 0.00121
   θ 0.00076 0.00076 0.00066 0.00101 0.00101 0.00088
   D 1.03138 1.19760 1.38242 0.83180 -0.03929 0.74751
  1. Estimate of nucleotide diversity per site from aaverage pairwise difference among individuals and bnumber of segregating sites (S); cTajima's D statistics; dn = 25 for normotensives, n = 25 for hypertensives; NA – not applicable