Polymorphism of the FABP2 gene: a population frequency analysis and an association study with cardiovascular risk markers in Argentina

Table 2 Association analysis of the Thr54 polymorphism and phenotypic parameters

Phenotypic parameters and threshold values	OR	CI (p = 0.05)	Significance
Cholesterol > 240 mg/ml	2.01	0.87–4.65	NS
BMI>24 kg/m2	1.44	0.7–2.98	NS
Cardiovascular risk >9	1.25	0.62–2.5	NS
Diastolic blood pressure > 90 mmHg	0.93	0.51–1.69	NS
Systolic blood pressure > 140 mmHg	0.86	0.44–1.47	NS
Glycemia > 140 mg/dl postprandial	0.76	0.33–1.76	NS

ORs were calculated as ratio between polymorphism carriers and non-carriers with high blood pressure (>140 mmHg systolic or 90 mmHg diastolic), high Framingham Risk Index (>9) high cholesterol (> 240 mg/dl), high BMI (>24 kg/m2), and high glycemia (>110 mg/dl after 8 h fasting or >140 postprandial mg/dl). 95% Confidence Intervals for p = 0.05 are shown. All CI include OR = 1, indicating no significant association between the polymorphism and the parameters tested.

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