Table 2 Genes with increased expression levels on microarrays in B-allele mutants, supported by qRT-PCR and/or ChIP Data
From: Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets
Gene Symbol | Gene Name | Function | Genomic Locus | Age | Fold Increase |
|---|---|---|---|---|---|
Irak1 | Interleukin-1 receptor-associated kinase 1 | Proinflammatory cytokine response, neuroprotection | X A7.3 | 8 wk | 2.2 |
Fxyd1 | FXYD domain-containing ion transport regulator 1 | Ion transport regulator for Na, K-ATPase | 7 B1 | 8 wk | 1.4 |
Reln | Reelin | Neuronal layer formation, cell-cell interactions | 5 A3-B1 | 2 wk | 1.5 |
Gtl2 | GTL2, imprinted maternally expressed untranslated RNA | Growth suppressor, Host gene for snoRNAs and microRNAs | 12 F1 | 2 wk 8 wk | 1.6 1.7 |