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Table 2 Interaction of diabetes mellitus and E-selectin polymorphism in coronary artery disease

From: The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease

Interaction Total Controls n = 854 CAD n = 2224 odds ratio (95% C.I) P value
No diabetes * S allele 422 256 166 Reference -
No diabetes * R allele 44 24 20 1.28 [.69–2.4] 0.431
diabetes * S allele 2458 543 1915 5.44 [4.4–6.7] < 0.001
diabetes * R allele 154 31 123 6.11 [3.9–9.5] < 0.001
  1. The data for the interaction between the S128R mutation and type 2 diabetes mellitus with regard to susceptibility of diabetic patients to acquiring coronary artery disease are presented in a 2 × 4 table. The four possible combinations of genotype and exposure are given in the first column of the table, and three categories of joint exposure are compared with the reference category of No diabetes * S allele.