Table 4 Causes of death according to COMT genotypes
Met/Met (n = 951) | Met/Val (n = 1482) | Val/Val (n = 546) | Val/Val vs. other genotypes | ||||
|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | Log-rank p value | |
Neoplasms (C00-D48) | 35 | 3.7 | 52 | 3.5 | 18 | 3.3 | 0.74 |
Cancers in the digestive system (C00-C26) | 14 | 1.5 | 14 | 0.9 | 4 | 0.7 | 0.39 |
Cancer in the respiratory system (C30-C39) | 6 | 0.6 | 11 | 0.7 | 1 | 0.2 | 0.23 |
Breast cancer/cancer in female genital organs (C50-C58) | 2 | 0.2 | 2 | 0.1 | 1 | 0.2 | 1.00 |
Prostate cancer (C61) | 5 | 0.5 | 10 | 0.7 | 6 | 1.1 | 0.24 |
All other neoplasms | 8 | 0.8 | 15 | 1.0 | 6 | 1.1 | 0.92 |
Cardiovascular causes (I00-I99) | 58 | 6.1 | 92 | 6.2 | 32 | 5.9 | 0.77 |
Ischemic heart diseases (I20-I25) | 29 | 3.0 | 43 | 2.9 | 15 | 2.7 | 0.78 |
Non-ischemic heart diseases (I30-I33 and I39-I52)# | 12 | 1.3 | 20 | 1.3 | 2 | 0.4 | 0.06 |
Cerebrovascular diseases (I60-I69) | 10 | 1.1 | 19 | 1.3 | 9 | 1.6 | 0.39 |
All other vascular deaths | 7 | 0.7 | 10 | 0.7 | 6 | 1.1 | 0.33 |
Sudden death (R96) | 1 | 0.1 | 3 | 0.2 | 1 | 0.2 | 0.92 |
Accidents (V01-V99, W00-W99, and X00-X99) | 7 | 0.7 | 10 | 0.7 | 5 | 0.9 | 0.87 |
Dementia (F03, G30, and R54) | 7 | 0.7 | 6 | 0.4 | 1 | 0.2 | 0.49 |
Diseases of the respiratory system (J00-J99) | 12 | 1.3 | 13 | 0.9 | 5 | 0.9 | 0.95 |
Diseases of the digestive system (K00-K93) | 3 | 0.3 | 7 | 0.5 | 4 | 0.7 | 0.33 |
Diseases of the kidney and ureter (N00-99) | 3 | 0.3 | 5 | 0.3 | 0 | 0 | 0.31 |
Other diseases* | 3 | 0.3 | 9 | 0.6 | 3 | 0.5 | 0.87 |