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Table 3 Mortality from various causes by January 1, 2005 related to COMT genotypes and 5- and 10-year survival.

From: The impact of the Catechol-O-methyltransferase Val158Met polymorphism on survival in the general population – the HUNT study

  Met/Met (n = 951) Met/Val (n = 1482) Val/Val (n = 546) 5-year survival 10-year survival
  n % n % n % p* p*
Genotypes         
Total deaths 129 32.7 197 49.8 69 17.5 0.77 0.87
Neoplasms (C00-D48) 35 33.3 52 49.5 18 17.1 0.97 0.93
Cardiovascular causes (I00-I99) 58 31.9 92 50.5 32 17.6 0.47 0.96
All other causes 36 33.3 53 49.1 19 17.6 0.72 0.94
Alleles Met   Val      
Total deaths 455 57.6 335 42.4    0.35 0.63
Neoplasms (C00-D48) 122 58.1 88 41.9    0.74 0.48
Cardiovascular causes (I00-I99) 208 57.1 156 42.9    0.30 0.57
All other causes 125 57.9 91 42.1    0.98 0.51
  1. * p value for the log-rank test