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Table 3 Mortality from various causes by January 1, 2005 related to COMT genotypes and 5- and 10-year survival.

From: The impact of the Catechol-O-methyltransferase Val158Met polymorphism on survival in the general population – the HUNT study

 

Met/Met (n = 951)

Met/Val (n = 1482)

Val/Val (n = 546)

5-year survival

10-year survival

 

n

%

n

%

n

%

p*

p*

Genotypes

        

Total deaths

129

32.7

197

49.8

69

17.5

0.77

0.87

Neoplasms (C00-D48)

35

33.3

52

49.5

18

17.1

0.97

0.93

Cardiovascular causes (I00-I99)

58

31.9

92

50.5

32

17.6

0.47

0.96

All other causes

36

33.3

53

49.1

19

17.6

0.72

0.94

Alleles

Met

 

Val

     

Total deaths

455

57.6

335

42.4

  

0.35

0.63

Neoplasms (C00-D48)

122

58.1

88

41.9

  

0.74

0.48

Cardiovascular causes (I00-I99)

208

57.1

156

42.9

  

0.30

0.57

All other causes

125

57.9

91

42.1

  

0.98

0.51

  1. * p value for the log-rank test