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Table 2 Clinical characteristics of the subjects according to COMT genotypes.

From: The impact of the Catechol-O-methyltransferase Val158Met polymorphism on survival in the general population – the HUNT study

Characteristics No COMT genotyping (n = 62,247) Met/Met (n = 951) Met/Val (n = 1482) Val/Val (n = 546)
Sex, female (%) 53.2 54.0 55.1 55.1
Age, mean (SD) 49.1(18.9)$ 52.8 (18.3) 52.7 (18.2) 52.1 (18.0)
Education > 12 years (%) 19.0 17.4 15.7 16.7
Mean systolic blood pressure (mmHg)(SD) 137.6 (22.3)$ 140.9 (22.2) 140.4 (22.6) 141.6 (22.9)
Mean diastolic blood pressure (mmHg)(SD) 80.2 (12.5)$ 81.7 (12.4) 81.0 (12.6) 82.3 (12.9)
Body mass index, kg/m2 (SD) 26.4 (4.1) 26.3 (4.2) 26.4 (4.1) 26.3 (4.2)
Cholesterol, mmol (SD) 5.89(1.26)$ 6.02 (1.31) 6.03 (1.30) 6.08 (1.37)
Current smoking (%) 29.0 28.0 29.6 29.0
High level of physical activity* (%) 24.1 19.9 18.7 20.1
Coffee intake > 6 cups/day (%) 20.1 19.6 18.6 19.0
Use of antihypertensive medication (%) 11.0 12.6 13.3 11.2
Myocardial infarction (%) 3.3 3.7 3.5 2.8
Angina pectoris (%) 5.0 6.9 7.1 5.9
Stroke (%) 1.9 2.5 1.6 1.8
  1. * High level of physical activity was defined as high intensity exercise more than 1 hour per week.
  2. $ p < 0.05