Figure 5From: High occurrence of BRCA1 intragenic rearrangements in hereditary breast and ovarian cancer syndrome in the Czech Republic Pedigrees of breast cancer family with detected deletion of BRCA1 exons 21–22 (g.77128_80906del3779ins236). Circles – females, squares – males, partially filled symbols – affected individuals, arrow – proband. Type of cancer and age of onset are indicated below each affected individual (br – breast). Mutation status: + carrier, - no carrier (wt).Back to article page