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Table 4 Haplotypes frequencies in cases and controls

From: The effect of ABCA1gene polymorphisms on ischaemic stroke risk and relationship with lipid profile

Haplotype

Controls

No. (%)

Cases

No. (%)

Crude OR

(95% CI)

p-value for crude OR

Adjusted* OR (95% CI)

p-value for adjusted OR

1111

591 (60.68)

463 (57.88)

0.89

(0.74–1.08)

0.232

0.94

(0.75–1.19)

0.611

1112

92 (9.45)

75 (9.38)

0.99

(0.72 – 1.37)

0.960

0.94

(0.64 – 1.38)

0.751

2211

80 (8.21)

88 (11.00)

1.38

(1.01 – 1.90)

0.047

1.40

(0.95 – 2.07)

0.086

2222

56 (5.75)

31 (3.88)

0.66

(0.42 – 1.04)

0.071

0.75

(0.43 – 1.28)

0.284

2212

54 (5.54)

56 (7.00)

1.28

(0.87 – 1.89)

0.207

1.27

(0.79 – 2.04)

0.315

2221

52 (5.34)

55 (6.88)

1.31

(0.89 – 1.94)

0.177

1.12

(0.70 – 1.78)

0.650

1211

12 (1.23)

20 (2.50)

2.06

(1.00–4.23)

0.050

1.46

(0.61 – 3.53)

0.398

2111

10 (1.03)

7 (0.88)

0.85

(0.32 – 2.25)

0.744

0.63

(0.16 – 2.38)

0.492

Others$

27 (2.78)

5 (0.63)

0.22

(0.09 – 0.57)

0.002

0.29

(0.10 – 0.82)

0.020

Total Alleles

974

800

    
  1. * ORs adjusted for age, gender, hypertension, triglyceride, HDL, total cholesterol and diabetes.
  2. $ Less frequent haplotypes