Table 3 lipid profiles changes in different ABCA1 genotypes and allele carriers:
From: The effect of ABCA1gene polymorphisms on ischaemic stroke risk and relationship with lipid profile
A. Lipid profile in carriers of different ABCA1 gene alleles in the whole population (cases and controls altogether) | |||||||
|---|---|---|---|---|---|---|---|
| Â | Â | Carrier 1 (11+12) | Non car. (22) | p-value | Carrier 2 (22+12) | Non car. (11) | p-value |
ABCA1-6 | HDL | 1.3597 | 1.3605 | NS | 1.3655 | 1.3545 | NS |
| Â | LDL | 3.4775 | 3.5805 | NS | 3.4439 | 3.5273 | NS |
| Â | TC | 5.6951 | 5.8002 | NS | 5.6163 | 5.7877 | NS |
| Â | TG | 1.7831 | 1.7436 | NS | 1.6834 | 1.8690 | 0.017 |
ABCA1-3 | HDL | 1.3446 | 1.2960 | NS | 1.3566 | 1.3254 | NS |
| Â | LDL | 3.5526 | 3.7406 | NS | 3.5246 | 3.6108 | NS |
| Â | TC | 5.7511 | 5.7903 | NS | 5.6764 | 5.8295 | NS |
| Â | TG | 1.7837 | 1.6215 | NS | 1.6546 | 1.8804 | 0.005 |
ABCA1-5 | HDL | 1.3587 | 1.4355 | NS | 1.4073 | 1.3456 | NS |
| Â | LDL | 3.4945 | 3.4193 | NS | 3.4848 | 3.4956 | NS |
| Â | TC | 5.7044 | 5.6052 | NS | 5.6795 | 5.7095 | NS |
| Â | TG | 1.7832 | 1.5616 | NS | 1.6355 | 1.8233 | 0.014 |
ABCA1-4 | HDL | 1.3658 | 1.2838 | NS | 1.3338 | 1.3818 | NS |
| Â | LDL | 3.4783 | 3.6276 | NS | 3.5464 | 3.4413 | NS |
| Â | TC | 5.6993 | 5.7631 | NS | 5.7841 | 5.6434 | NS |
| Â | TG | 1.7690 | 1.7868 | NS | 1.7727 | 1.7679 | NS |
B. Lipid profile in carriers of different ABCA1 gene alleles in controls | |||||||
ABCA1-6 | HDL | 1.4429 | 1.4804 | NS | 1.4578 | 1.4350 | NS |
| Â | LDL | 3.4442 | 3.4792 | NS | 3.4147 | 3.4762 | NS |
| Â | TC | 5.8044 | 5.9003 | NS | 5.7374 | 5.8794 | NS |
| Â | TG | 1.8046 | 1.7877 | NS | 1.7099 | 1.8881 | NS |
ABCA1-3 | HDL | 1.4416 | 1.4097 | NS | 1.4681 | 1.4143 | NS |
| Â | LDL | 3.4805 | 3.5634 | NS | 3.4173 | 3.5464 | NS |
| Â | TC | 5.8415 | 5.8622 | NS | 5.7426 | 5.9319 | NS |
| Â | TG | 1.8264 | 1.7660 | NS | 1.7310 | 1.9042 | NS |
ABCA1-5 | HDL | 1.4473 | 1.3916 | NS | 1.4920 | 1.4311 | NS |
| Â | LDL | 3.4534 | 3.5611 | NS | 3.4592 | 3.4540 | NS |
| Â | TC | 5.8155 | 5.6472 | NS | 5.7071 | 5.8175 | NS |
| Â | TG | 1.8143 | 1.4965 | NS | 1.7026 | 1.8433 | NS |
ABCA1-4 | HDL | 1.4528 | 1.3398 | NS | 1.4143 | 1.4712 | NS |
| Â | LDL | 3.4343 | 3.5858 | NS | 3.5336 | 3.3742 | NS |
| Â | TC | 5.7987 | 5.8264 | NS | 5.8773 | 5.7429 | NS |
| Â | TG | 1.7965 | 1.8134 | NS | 1.7893 | 1.8036 | NS |
C. Lipid profile in different carriers of ABCA1 gene alleles in cases | |||||||
ABCA1-6 | HDL | 1.2357 | 1.2333 | NS | 1.2362 | 1.2348 | NS |
| Â | LDL | 3.5242 | 3.6879 | NS | 3.4813 | 3.6015 | NS |
| Â | TC | 5.4888 | 5.7000 | NS | 5.4662 | 5.6623 | NS |
| Â | TG | 1.7499 | 1.6923 | NS | 1.6447 | 1.8395 | NS |
ABCA1-3 | HDL | 1.2123 | 1.2107 | NS | 1.2217 | 1.2024 | NS |
| Â | LDL | 3.6464 | 3.8690 | NS | 3.6485 | 3.7008 | NS |
| Â | TC | 5.6403 | 5.7424 | NS | 5.6057 | 5.7004 | NS |
| Â | TG | 1.7236 | 1.5037 | NS | 1.5596 | 1.8459 | 0.017 |
ABCA1-5 | HDL | 1.2319 | 1.4857 | NS | 1.2691 | 1.2288 | NS |
| Â | LDL | 3.5502 | 3.2571 | NS | 3.5243 | 3.5494 | NS |
| Â | TC | 5.5619 | 5.5571 | NS | 5.5079 | 5.5766 | NS |
| Â | TG | 1.7372 | 1.6483 | NS | 1.5243 | 1.7948 | 0.016 |
ABCA1-4 | HDL | 1.2452 | 1.1867 | NS | 1.2169 | 1.2603 | NS |
| Â | LDL | 3.5358 | 3.7000 | NS | 3.5640 | 3.5282 | NS |
| Â | TC | 5.5760 | 5.6533 | NS | 5.6622 | 5.5212 | NS |
| Â | TG | 1.7292 | 1.7407 | NS | 1.7480 | 1.7166 | NS |