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Table 2 Total and village specific prevalence of selected traits, with 95% Confidence Intervals (95%CI) and Fisher's exact test p-value

From: The genetic study of three population microisolates in South Tyrol (MICROS): study design and epidemiological perspectives

Qualitative Traits

 

All

 

Stelvio

 

Martello

 

Vallelunga

  
  

Prev

95%CI

Prev

95%CI

Prev

95%CI

Prev

95%CI

p-value

Symptoms for cardiovascular disease

Elevated Blood Pressure

17.7

(15.5, 20.0)

17.5

(14.3, 21.0)

24.8

(20.2, 29.8)

10.5

(7.4, 14.4)

< 0.0001

 

Cardiac Arrhythmias

19.5

(17.3, 21.9)

16.8

(13.7, 20.2)

25.2

(20.7, 30.1)

17.8

(13.8, 22.5)

0.0067

 

Angina pectoris

16.7

(14.6, 19.0)

11.9

(9.2, 14.9)

26.5

(22.0, 31.4)

13.9

(10.3, 18.2)

< 0.0001

 

Cardiac Disease

2.5

(1.7, 3.6)

1.9

(0.9, 3.5)

3.7

(2.0, 6.3)

2.2

(0.9, 4.5)

0.2476

 

Myocardial Infarction

1.2

(0.6, 2.0)

1.3

(0.5, 2.7)

1.4

(0.5, 3.3)

0.6

(0.1, 2.3)

0.6176

 

Heart Defects

3.2

(2.3, 4.4)

2.8

(1.6, 4.6)

4.0

(2.2, 6.6)

2.9

(1.3, 5.4)

0.5882

Neurological traits

Vertigo

32.0

(29.3, 34.7)

34.4

(30.3, 38.6)

27.5

(22.8, 32.5)

33.0

(27.9, 38.5)

0.0900

 

Migraine

20.8

(18.6, 23.2)

20.5

(17.1, 24.2)

25.1

(20.7, 30.0)

16.6

(12.6, 21.1)

0.0244

 

Carpal Tunnel Syndrome symptoms

14.8

(12.7, 17.1)

20.2

(16.2, 24.6)

12.0

(8.8, 15.9)

11.5

(8.2, 15.5)

0.0017

 

Restless Leg's Syndrome (RLS)

12.8

(10.9, 14.8)

13.3

(10.5, 16.6)

12.6

(9.3, 16.6)

12.0

(8.7, 16.1)

0.8729

 

Vascular Problems in the Carotid Arteries

2.9

(2.0, 4.0)

2.3

(1.2, 4.0)

3.5

(1.8, 6.0)

3.2

(1.5, 5.8)

0.5677

 

Stroke

1.7

(1.0, 2.6)

1.2

(0.4, 2.5)

2.6

(1.2, 4.8)

1.6

(0.5, 3.7)

0.2714

 

Epilepsy

2.0

(1.3, 3.0)

2.7

(1.5, 4.4)

2.0

(0.8, 4.1)

1.0

(0.2, 2.8)

0.2337

Symptoms related to the respiratory system, allergy and dermatology

Asthma

4.2

(3.1, 5.5)

4.8

(3.1, 7.0)

4.3

(2.4, 7.0)

3.2

(1.5, 5.8)

0.5566

 

Chronic Bronchitis

5.2

(4.0, 6.6)

5.1

(3.4, 7.4)

6.9

(4.4, 10.0)

3.5

(1.8, 6.2)

0.1519

 

Hay Fever

8.3

(6.8, 10.0)

9.4

(7.0, 12.2)

6.3

(4.0, 9.4)

8.6

(5.7, 12.3)

0.2586

 

Insect Hypersensitivity

12.7

(10.9, 14.7)

12.6

(9.9, 15.7)

12.4

(9.1, 16.3)

13.3

(9.8, 17.6)

0.9252

 

Eczema

3.9

(2.9, 5.1)

5.3

(3.6, 7.6)

3.5

(1.8, 6.0)

1.9

(0.7, 4.1)

0.0403

 

Psoriasis

3.2

(2.3, 4.4)

3.6

(2.2, 5.6)

2.0

(0.8, 4.1)

3.8

(2.0, 6.5)

0.3134

Other traits

Diabetes

3.6

(2.6, 4.9)

3.5

(2.1, 5.4)

4.9

(2.9, 7.7)

2.5

(1.1, 4.9)

0.2680

 

Goitre

6.4

(5.1, 7.9)

5.9

(4.0, 8.3)

7.7

(5.2, 11.0)

5.7

(3.4, 8.9)

0.4865

 

Gout or Hyperuricemia

3.5

(2.5, 4.7)

3.6

(2.2, 5.6)

4.6

(2.6, 7.3)

1.9

(0.7, 4.1)

0.1470

 

Gallbladder Disease

10.7

(9.0, 12.9)

12.2

(9.5, 15.3)

10.9

(7.8, 14.6)

7.9

(5.2, 11.5)

0.1454

 

Ulcer

9.3

(7.7, 11.1)

10.7

(8.2, 13.7)

8.0

(5.4, 11.4)

8.3

(5.5, 11.9)

0.3280

 

Liver Disease

6.3

(5.0, 7.9)

6.1

(4.2, 8.6)

9.2

(6.4, 12.8)

3.5

(1.8, 6.2)

0.0102

 

Kidney Disease

13.6

(11.7, 15.7)

13.1

(10.3, 16.3)

14.7

(11.1, 18.8)

13.3

(9.8, 17.6)

0.7877

 

Anemia

6.5

(5.1, 8.0)

5.8

(3.9, 8.2)

8.5

(5.8, 12.0)

5.4

(3.2, 8.5)

0.2038