Pedigree of the family affected with LFSNHL and audiogram of three chosen affected individuals. In the pedigree, shaded symbols indicate family members affected by LFSNHL, while open symbols indicate those with a normal hearing. An autosomal dominant hereditary pattern is shown in this pedigree. Pure tone audiograms of I:2, II:1, and II:3 show a predominantly bilateral low-tone hearing impairment. Circles and crosses indicate air conduction in the right and left ears respectively.