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Figure 1 | BMC Medical Genetics

Figure 1

From: Transient trimethylaminuria related to menstruation

Figure 1

Decreased metabolic capacity of FMO3 (), as indicated as percent free trimethylamine (TMA, ) to total trimethylamine () excreted in the urine, in relation to menstruation. Filled boxes indicate the period of menstruation. Total urinary trimethylamine and free trimethylamine concentrations were calculated as mmol trimethylamine (TMA)/mol creatinine. Cases (A) and (B) were self-reported subjects suffering from malodour genotyped for homozygotic inactive Arg500stop FMO3 and homozygotic common [Glu158Lys; Glu308Gly] FMO3, respectively. Cases (C) and (D and E) were control subjects genotyped as heterozygotic for [Glu158Lys; Glu308Gly] FMO3 and homozygotic for wild FMO3, respectively.

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