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Figure 5 | BMC Medical Genetics

Figure 5

From: Analysis of meiotic recombination in 22q11.2, a region that frequently undergoes deletions and duplications

Figure 5

Hotspot prediction and comparison between historical and contemporary recombination rates in two regions of high marker density in the pedigree-based map. Charts a-d are for the region between positions 17,80 and 18,40 Mb and e-h for the region between positions 20,60 and 21,00 Mb. In all charts recombination rates based on family data are shown in red. Charts a and e shows the prediction of hotspot intensity and location (PHASE 2.1.1 software, -MR1 option) in the region. Charts b and f show population recombination rate profile (PHASE 2.1.1 software, -MR0 option) based on our analysis. Charts c and g show population recombination rate profiles as shown in the UCSC genome web tracks based on Hapmap data. Charts d and h show population recombination rate profiles as shown in the UCSC genome web tracks based on Perlegen data.

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