Table 1 Effect on BRCAPRO Carrier Probability of Ignoring vs. Including Oophorectomy for Families Based on Figure 1.
From: Incorporating medical interventions into carrier probability estimation for genetic counseling
Family | Ignoring all Oophorectomies | Including all Oophorectomies |
|---|---|---|
As in Figure 1 | 3% | 13% |
No oophorectomy for sister | 3% | 12% |
No oophorectomy for mother | 3% | 4% |
Sister has breast cancer at 56 | 11% | 29% |
Sister has peritoneal cancer at 56 | 25% | 44% |
Mother has only breast cancer at 80 | 1% | 1.4% |