Table 4 Statistically significant associations between the different SNPs and clinico-pathological variables
From: Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanoma
Genotype | p-value | ||
|---|---|---|---|
Q279R | QQ (reference) | QR + RR | |
Intransit Metastasis | |||
Yes | 17 (63%) | 10 (37%) | |
No | 384 (41%) | 557 (59%) | p = 0.03; p = 0.02¥ |
Tan/Burn Tendency | |||
Tend to Tan | 26 (29%) | 65 (71%) | |
Tend to Sunburn | 394 (43%) | 516 (57%) | p < 0.01; p < 0.01¥ |
P574R | PP (reference) | PR + RR | |
Site | |||
Extremities | 263 (88%) | 36 (12%) | |
Trunk | 164 (96%) | 7 (4%) | |
Head & Neck | 36 (97%) | 1 (3%) | |
Non-cutaneous | 6 (100%) | 0 (0%) | p = 0.01; p = 0.02¥ |
R668Q | RR (reference) | RQ + QQ | |
Tan/Burn Tendency | |||
Tend to Tan | 55 (60%) | 36 (40%) | |
Tend to Sunburn | 661 (73%) | 245 (27%) | p = 0.01; p = 0.02¥ |