Table 5 Effects of the main haplotypes of CAPN5 by comparison to the most frequent haplotype adjusted for age and sex
From: Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels
TRAIT | HAPLOTYPE | MEAN EFFECT [CI] (%) | P | χ2 5d.f | PGLOBAL |
|---|---|---|---|---|---|
BMI (kg/m2) | AA-CA | 0.66 [-0.10 – 1.42] (+ 5.9%) | 0.089 | 10.75 | 0.056 |
DBP (mmHg) | GG-CG | -2.22 [-3.82 – -0.62] (- 6.1%) | 0.006 | 14.96 | 0.010 |
AG-CA | -5.18 [-8.08 – -2.28] (- 14.2%) | 0.0005 | |||
Cholesterol (mg/dl) | GG-CG | -7.98 [-15.18 – -0.79] (- 8.0%) | 0.029 | 11.43 | 0.043 |
GG-CA | 29.41 [11.66 – 47.17 ] (+ 29.6%) | 0.001 |