Figure 1

Percent of T2DM patients for each genotype ( UCP3 and ADRB2-16 )and age group in non-obeseparticipants. On the x-axis the three main age ranges are indicated. The bars indicate the frequencies of non-obese subjects that develop diabetes according to their age range and genotype. Black bars included all the UCP3 T and ARDB2-16 Arg carriers. White bars represent the double homozygote UCP3 CC/ARDB2-16 GlyGly. UCP3 T/ARDB2-16 Arg carriers individuals show an age-related increased frequency of diabetic disease, while double-homozygotes do not. Number of diabetic patients and number of total subjects, divided by a slash, are at the bottom of the bar of each class.