Triglyceride associated polymorphisms of the APOA5gene have very different allele frequencies in Pune, India compared to Europeans

Table 2 Prevalence of APOA5 gene variants -1131T>C and S19W in Asian Indians and UK white subjects.

SNP	-1131T>C					S19W
	TT	TC	CC	Carrier* Frequency (95% CIs)	Less common allele Frequency (95% CIs)	SS	SW	WW	Carrier* Frequency (95% CIs)	Less common allele Frequency (95% CIs)
Pune Indians (n = 524)	336	170	18	0.36 (0.32–0.40)	0.20 (0.17–0.22)	497	27	0	0.05 (0.03–0.07)	0.03 (0.02–0.04)
UK whites (n = 237)	218	19	0	0.08 (0.05–0.11)	0.04 (0.02–0.06)	210	26	1	0.11 (0.07–0.15)	0.06 (0.04–0.08)
P value					<0.00001					0.0015

Asian Indians (adults from the Pune Children Study) and UK white subjects (adults from the Plymouth EarlyBird study).
P values are calculated for differences in genotype frequencies between Pune Indians and UK white subjects. *Carrier frequency indicates individuals carrying at least one copy of the less common allele at either polymorphism. Neither population showed any deviation from HWE for either polymorphism (p > 0.05).

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