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Table 2 Unadjusted associations between SNPs from surfactant protein A alleles (SP-A1, SP-A2) and otitis media (OM) episodes before 12 months of age for 355 infants at risk for developing asthma. (CT and MA, 1998 – 2000)

From: Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma

   OM Episodes
SNP n (%) %
All subjects N (%) 355 258 (72.7)
SP-A1 a   
   aa 19 b   
CC 1 (0.3)  
CT 56 (15.8) 89.5
TT 294 (83.8) 69.0
   aa 50   
CC 75 (21.2) 80.0
CG 171 (48.3) 69.0
GG 108 (30.5) 74.1
   aa 62   
GG 5 (1.4)  
AG 88 (25.2) 74.2
AA 256 (73.4) 71.9
   aa 133   
GG 2 (0.6)  
AG 51 (14.4) 83.0
AA 302 (85.1) 70.9
   aa 219   
TT 1 (0.3)  
CT 46 (13.0) 68.1
CC 308 (86.8) 73.4
SP-A2 a   
   aa 9   
CC 73 (20.6) 74.0
AC 171 (48.2) 71.9
AA 111 (31.3) 73.0
   aa 91   
CC 6 (1.7)  
CG 85 (24.2) 73.6
GG 261 (74.2) 72.4
   aa 140   
TT 25 (7.1) 64.0
CT 142 (40.2) 71.1
CC 186 (52.7) 75.3
   aa 223   
AA 18 (5.1) 77.8
AC 129 (36.3) 72.9
CC 208 (58.6) 72.1
  1. aEach of the SNPs was in Hardy-Weinberg equilibrium (P > 0.05).
  2. bP = 0.02, χ2-test.