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Table 2 Unadjusted associations between SNPs from surfactant protein A alleles (SP-A1, SP-A2) and otitis media (OM) episodes before 12 months of age for 355 infants at risk for developing asthma. (CT and MA, 1998 – 2000)

From: Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma

  

OM Episodes

SNP

n (%)

%

All subjects N (%)

355

258 (72.7)

SP-A1 a

  

   aa 19 b

  

CC

1 (0.3)

 

CT

56 (15.8)

89.5

TT

294 (83.8)

69.0

   aa 50

  

CC

75 (21.2)

80.0

CG

171 (48.3)

69.0

GG

108 (30.5)

74.1

   aa 62

  

GG

5 (1.4)

 

AG

88 (25.2)

74.2

AA

256 (73.4)

71.9

   aa 133

  

GG

2 (0.6)

 

AG

51 (14.4)

83.0

AA

302 (85.1)

70.9

   aa 219

  

TT

1 (0.3)

 

CT

46 (13.0)

68.1

CC

308 (86.8)

73.4

SP-A2 a

  

   aa 9

  

CC

73 (20.6)

74.0

AC

171 (48.2)

71.9

AA

111 (31.3)

73.0

   aa 91

  

CC

6 (1.7)

 

CG

85 (24.2)

73.6

GG

261 (74.2)

72.4

   aa 140

  

TT

25 (7.1)

64.0

CT

142 (40.2)

71.1

CC

186 (52.7)

75.3

   aa 223

  

AA

18 (5.1)

77.8

AC

129 (36.3)

72.9

CC

208 (58.6)

72.1

  1. aEach of the SNPs was in Hardy-Weinberg equilibrium (P > 0.05).
  2. bP = 0.02, χ2-test.