BMC Medical Genetics

Table 6 Analysis of HLA loci in AAA cases and controls when stratified by family history of AAA

From: Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study

Locus	Belgian				Canadian
	Family history		No family history		Family history		No family history
	EP^a	AP^b	EP^a	AP^b	EP^a	AP^b	EP^a	AP^b
DQA1	0.069	0.067	0.157	0.164	0.198	0.284	0.764	0.832
DQB1	0.419	0.415	0.305	0.317	0.384	0.532	0.432	0.571
DRB1	0.597	0.811	0.099	0.171	0.232	0.545	0.242	0.659
DRB3-5	0.356	0.454	0.314	0.414	0.831	0.796	0.490	0.581

AAA: abdominal aortic aneurysm; EP: empirical p-value; AP: asymptotic p-value.
^a Global empirical p-values were calculated by permutation test using the CLUMP [28] program.
^b Asymptotic p-values were calculated by χ² test.

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ISSN: 1471-2350

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