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Table 5 Empirical and asymptotic p-values for comparisons between AAA cases and controls within each population and stratified by sex

From: Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study

Locus

Belgian

Canadian

 

Malea

Femalea

Total

Malea

Femalea

Total

 

EPb

APc

EPb

APc

EPb

APc

EPb

APc

EPb

APc

EPb

APc

DQA1

0.027

0.071

0.899

0.900

0.039

0.049

0.392

0.487

0.340

0.443

0.589

0.682

DQB1

0.083

0.130

0.495

0.710

0.129

0.144

0.917

0.972

0.405

0.553

0.371

0.510

DRB1

0.252

0.375

0.218

0.653

0.114

0.200

0.465

0.890

0.408

0.864

0.246

0.545

DRB3-5

0.145

0.217

0.239

0.308

0.217

0.308

0.745

0.778

0.926

0.952

0.766

0.739

  1. AAA: abdominal aortic aneurysm; EP: empirical p-value; AP: asymptotic p-value.
  2. a Number of Belgian AAA cases: Male = 161, Female = 19; Canadian AAA cases: Male = 155, Female = 52; Belgian controls: Male = 178, Female = 91; Canadian controls: Male = 39, Female = 118.
  3. b Global empirical p-values were calculated by permutation test using the CLUMP [28] program.
  4. c Asymptotic p-values were calculated by χ2 test.