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Table 4 HLA-DRB3-5 allele frequencies in AAA cases and controls

From: Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study

 

AAA Cases

Controls

 

Male

Female

Total

Male

Female

Total

DRB3-5 alleles

na

%

na

%

na

%

na

%

na

%

na

%

Belgian

B3*0101

40

12.5

8

22.2

48

13.5

53

14.8

24

14.4

77

14.6

B3*0201

11

3.4

1

2.8

12

3.4

11

3.1

0

0

11

2.1

B3*0202

63

19.7

8

22.2

71

19.9

86

24.0

35

21.0

121

23.0

B3*0301

34

10.6

7

19.4

41

11.5

45

12.5

22

13.2

67

12.7

B4*0101

94

29.4

7

19.4

101

28.4

103

28.7

52

31.1

155

29.5

B5*0101

50

15.6

2

5.6

52

14.6

31

8.6

16

9.6

47

8.9

B5*0102

4

1.3

0

0

4

1.1

2

0.6

3

1.8

5

1.0

B5*0201

7

2.2

0

0

7

2.0

6

1.7

1

0.6

7

1.3

B5*0203

0

0

0

0

0

0.0

0

0

0

0

0

0

B3*0201 or *0202 b

13

4.1

1

2.8

14

3.9

20

5.6

10

6.0

30

5.7

CND

4

1.3

2

5.6

6

1.7

2

0.6

4

2.4

6

1.1

Total

320

100.0

36

100.0

356

100.0

359

100.0

167

100.0

526

100.0

Canadian

B3*0101

53

17.2

17

17

70

17.2

9

13.6

38

15.3

47

15.0

B3*0201

9

2.9

5

5.0

14

3.4

0

0

6

2.4

6

1.9

B3*0202

44

14.3

15

15

59

14.5

8

12.1

46

18.5

54

17.2

B3*0301

38

12.3

13

13

51

12.5

11

16.7

32

12.9

43

13.7

B4*0101

108

35.1

32

32

140

34.3

26

39.4

80

32.3

106

33.8

B5*0101

45

14.6

14

14

59

14.5

12

18.2

38

15.3

50

15.9

B5*0102

1

0.3

1

1.0

2

0.5

0

0

3

1.2

3

1.0

B5*0201

2

0.6

1

1.0

3

0.7

0

0

1

0.4

1

0.3

B5*0203

1

0.3

0

0

1

0.2

0

0

0

0

0

0

B3*0201 or *0202 b

3

1.0

0

0

3

0.7

0

0

0

0

0

0

CND

4

1.3

2

2.0

6

1.5

0

0

4

1.6

4

1.3

Total

308

100.0

100

100.0

408

100.0

66

100.0

248

100.0

314

100.0

  1. AAA: abdominal aortic aneurysm; CND: could not be determined.
  2. a Number of alleles.
  3. b Could be classified into HLA-DRB*0201 or *0202, but could not be classified into one particular allele.