Table 2 NAT2 genotypes in controls and lung cancer patients
From: N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients
Genotypes | Deduced phenotypes | Controls | Lung cancer | Total | Odds ratios (95% confidence interval)2 | ||
|---|---|---|---|---|---|---|---|
c.481 C>T | c.590 G>A | c.857 G>A | Â | n = 243 | n = 67 | n = 310 | Â |
CC | GG | GG | rapid | 5.3% (13) | 7.5% (5) | 5.8% (18) | reference |
CT |  |  | rapid | 23.0% (56) | 13.4% (9) | 21.0% (65) | 0.42 (0.12–1.46) |
|  | GA |  | rapid | 8.6% (21) | 20.9% (14) | 11.3% (35) | 1.73 (0.50–5.95) |
| Â | Â | GA | rapid | 0.4% (1) | 0 | 0.3% (1) | Â |
TT |  |  | slow1 | 22.2% (54) | 13.4% (9) | 20.3% (63) | 0.43 (0.12–1.51) |
| Â | AA | Â | slow | 9.5% (23) | 0 | 7.4% (23) | Â |
| Â | Â | AA | slow | 0 | 0 | 0 | Â |
| Â | AA | GA | slow | 4.1% (10) | 0 | 3.2% (10) | Â |
CT | GA |  | slow | 23.9% (58) | 38.8% (26) | 27.1% (84) | 1.17 (0.38–3.60) |
CT |  | GA | slow | 2.5% (6) | 4.5% (3) | 2.8% (9) | 1.30 (0.23–7.31) |
|  | GA | GA | slow | 0.4% (1) | 1.4% (1) | 0.6% (2) | 2.60 (0.14–50.04) |