Table 1 NAT2 genotypes in controls and colon cancer patients
From: N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients
Genotypes | Deduced phenotypes | Controls | Colon cancer | Total | Odds ratios (95% confidence interval)2 | ||
|---|---|---|---|---|---|---|---|
c.481 C>T | c.590 G>A | c.857 G>A | Â | n = 243 | n = 92 | n = 335 | Â |
CC | GG | GG | rapid | 5.4% (13) | 9.8% (9) | 6.6% (22) | reference |
CT |  |  | rapid | 23.0% (56) | 18.5% (17) | 21.8% (73) | 0.44 (0.16–1.20) |
|  | GA |  | rapid | 8.6% (21) | 13.0% (12) | 9.9% (33) | 0.83 (0.27–2.49) |
|  |  | GA | rapid | 0.4% (1) | 2.2% (2) | 0.9% (3) | 2.89 (0.23–36.87) |
TT |  |  | slow1 | 22.2% (54) | 13.0% (12) | 19.7% (66) | 0.32 (0.11–0.92)** |
|  | AA |  | slow | 9.5% (23) | 13.0% (12) | 10.4% (35) | 0.75 (0.25–2.26) |
| Â | Â | AA | slow | 0 | 0 | 0 | Â |
| Â | AA | GA | slow | 4.1% (10) | 0 | 3.0% (10) | Â |
CT | GA |  | slow | 23.9% (58) | 29.3% (27) | 25.4% (85) | 0.67 (0.26–1.77) |
CT |  | GA | slow | 2.5% (6) | 1.0% (1) | 2.1% (7) | 0.24 (0.03–2.36) |
| Â | GA | GA | slow | 0.4% (1) | 0 | 0.3% (1) | Â |