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Table 2 ADRB3 genotype and BMD: Standardized regression coefficient from the multiple regression analyses

From: β3-adrenergic receptor gene, body mass index, bone mineral density and fracture risk in elderly men and women: the Dubbo Osteoporosis Epidemiology Study (DOES)

 

LSBMD

FNBMD

 

Coefficient

P value

Coefficient

P value

Women

    

   Age

-0.040

0.380

-0.344

<0.01

   BMI

0.366

<0.01

0.382

<0.01

   Smoking

-0.041

0.37

-0.087

0.03

   Calcium intake

-0.018

0.69

0.050

0.23

   Physical activity

0.140

<0.01

0.035

0.40

   ADRB3a

0.044

0.33

0.046

0.26

   R2

0.162

 

0.302

 

Men

    

   Age

-0.018

0.78

-0.187

<0.01

   BMI

0.231

<0.01

0.240

<0.01

   Smoking

-0.104

0.09

-0.149

<0.01

   Calcium intake

0.091

0.14

0.048

0.01

   Physical activity

0.124

0.05

0.036

0.43

   ADRB3a

0.001

0.99

0.003

0.60

   R2

0.074

 

0.120

 
  1. LSBMD, lumbar spine bone mineral density; FNBMD, femoral neck bone mineral density.
  2. R2: coefficient of determination; proportion of variance of BMD (LSBMD or FNBMD) accounted for by all the factors in the model. aNon-Arg allele carrier and Arg allele carrier.
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BMC Medical Genetics

ISSN: 1471-2350

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