The functional

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Table 2 Result of case/control and FBAT analyses for SNP F352V.

Genotype or Allele	Case-Control Analysis				FBAT
	Controls (N = 1619) Number (Frequency)	Cases (N = 1793) Number (Frequency)	Odds Ratio (95% CI)	P	Observed Transmissions (V allele)	Expected Transmissions (V allele)	P
FF	1158 (0.72)	1296 (0.72)
FV	409 (0.25)	447 (0.25)	0.98 (0.84–1.14)	0.74
VV	52 (0.03)	50 (0.03)	0.86 (0.58–1.28)		136	132	0.57
F	2725 (0.84)	3039 (0.85)
V	513 (0.16)	547 (0.15)	0.96 (0.84–1.09)	0.50

P values for the case-control analysis (two-tailed) were calculated using Chi-square tests with a 3 × 2 contingency table (genotypes; 2 d.f.) or a 2 × 2 contingency table (alleles; 1 d.f.). Odds ratios were calculated relative to genotype FF or allele F. CI, confidence interval.

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