Table 3 Mean and difference (95% CI) in body mass index (kg/m2) between individuals homozygous and heterozygous carriers of the 363S allele of the GRL gene and homozygotes for the N363 allele in studies with one population group
Study | 363S/N363 363S/363S | N363/N363 | Mean difference | % carriers | City, origin | Age, gender | Ref. | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | Mean BMI | n | Mean BMI | 95% CI | |||||||
Huizenga 98 | 12 | 28.1 | 198 | 26.6 | 1.5 | 1.3 | 1.7 | 5.7 | Rotterdam, Netherlands | 66–68, both | 6 |
Halsall 00 | 38 | 26.3 | 453 | 25.8 | 0.5 | 0.4 | 0.6 | 7.7 | Isle of Ely, UK | 54, NA | 7 |
Rosmond 01 | 25 | 26.0 | 243 | 26.2 | -0.2 | -1.8 | 1.4 | 9.3 | Gotenburg, Sweden | NA, men | 8 |
Dobson 01 | 23 | 26.1 | 352 | 26.6 | -0.5 | -2.6 | 1.7 | 6.1 | Newcastle, UK | 54, both | 9 |
Morris 03 | 46 | 41.7 | 122 | 45.0 | -3.3 | -6.3 | -0.3 | 27.4 | Sydney, Australia | NA, NA | 11 |
Rosmond 03 | 15 | 27.5 | 141 | 27.1 | 0.4 | -1.6 | 2.4 | 9.6 | Sävedalen, Sweden | NA, men | 10 |
Roussel 03 | 20 | 29.6 | 349 | 28.0 | 1.6 | -0.5 | 3.7 | 5.4 | Paris, France | 62, both | 12 |
Wüst 04 | 16 | 21.1 | 92 | 22.0 | -0.8 | -2.4 | 0.7 | 14.8 | Trier, Germany | 18, men | 14 |
Syed 04 | 2 | 28.2 | 293 | 27.1 | 1.1 | -5.3 | 7.4 | 0.7 | South Asian, UK | 51, both | 13 |
Total (n) | 197 | 2243 | |||||||||