Figure 1

Odds Ratios with the 95% CI for the association between presence of the N363S polymorphism of the GRL gene and the likelihood of being obese in the overall studies. In the study by Echwald et al (2001) only men were recruited from Copenhagen, Denmark, mean age = 45. The study by Lin et al (1999) included men (53%) and women (47%), mean age = 50, from Sydney (Australia), the study by Lin et al (2003) included men (80%) and women (20%), mean age = 45, from Sydney (Australia). The Navarra adults study enrolled men (20%) and women (80%), mean age = 40, from Navarra (North of Spain). The Navarra children study encompassed boys (53%) and girls (53%), mean age = 11 from Navarra (North of Spain). The German children study consisted of boys (50%) and girls (50%), mean age = 14 from West and South Germany. Test for heterogeneity Q = 24.2; 5 df; p < 0.01.