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Table 5 Previously reported transcription factor binding sites in the PI3 promoter.

From: Identification of novel functional sequence variants in the gene for peptidase inhibitor 3

Transcription factor      Evidencec
Gene Symbol Alias Positiona AL049767.12b Author PubMedID IS E DM
NFKB1 NFκB   48564–48581 King et al. 2003 14521952 +   
     Pol et al. 2003 12542536 +   +
   -479 – -470 49058–49067 King et al. 2003 14521952 +   
   -340 – -331 49197–49206 King et al. 2003 14521952 +   
   -164 – -153 49373–49384 Zhang 1995 7780965 +   +
     Bingle et al. 2001 11472979   + +
     King et al. 2003 14521952 +   
     Pol et al. 2003 12542536 +   +
JUN AP1 -545 – -537 48992–49000 Zhang 1995 7780965 +   +
     Zhang 1997 9377579   + +
     King et al. 2003 14521952 +   
     Pol et al. 2003 12542536 +   +
   -356 – -345 49181–49192 Sallenave et al. 1994 7946401 +   
     Pol et al. 2003 12542536 +   +
SP1   -82 – -74 49455–49463 Zhang 1995 7780965 +   +
     Pol et al. 2003 12542536 +   +
CEBPB NFIL6 -386 – -378 49151–49159 Pol et al. 2003 12542536 +   +
   -356 – -345 49181–49192 Pol et al. 2003 12542536 +   +
   -307 – -299 49230–49238 Pol et al. 2003 12542536 +   +
   -203 – -194 49334–49343 Sallenave et al. 1994 7946401 +   
     Pol et al. 2003 12542536 +   +
   -126 – -117 49411–49420 Pol et al. 2003 12542536 +   +
OCT1   -590 – -582 48947–48955 Zhang 1995 7780965 +   +
EST1 PEA-3 -484 – -479 49053–49058 Sallenave et al. 1994 7946401 +   
  1. aPosition is given relative to ATG.
  2. bWe have mapped the location used in the studies to the current GenBank sequence to standardize the numbering between all studies.
  3. cIS, in silico; E, EMSA; DM, deletion mapping.