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Table 2 Allele and genotype frequencies of RANTES, IL-8, MCP-1 and IL-1α polymorphisms in SLE patients and healthy controls.

From: Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus

  SLE patients Controls P OR (95%CI)
RANTES -403 n % n %   
Genotypes       
GG 369 73.8 333 69.3 0.1  
GA 113 22.6 135 28 0.04 0.75 (0.55–1.01)
AA 18 3.6 13 2.7 0.4  
Alleles       
G 851 85 801 83.3   
A 149 15 161 16.7 0.2  
RANTES R3 n % n %   
Genotypes       
CC 326 73.8 340 77.6 0.06  
CT 104 23.5 90 20.6 0.3  
TT 12 2.7 8 1.8 0.4  
Alleles       
C 756 85.5 770 88   
T 128 14.5 106 12 0.1  
IL-8 -353 n % n %   
Genoypes       
AA 126 28.7 125 30.3 0.6  
AT 215 49 194 47.1 0.5  
TT 98 22.3 93 22.6 0.9  
Alleles       
A 467 53.2 444 53.8   
T 411 46.8 380 46.2 0.7  
IL-8 +781 n % n %   
Genotypes       
CC 164 35 143 33.3 0.6  
CT 238 51 221 51.5 0.8  
TT 65 14 65 15.2 0.6  
Alleles       
C 566 60.6 507 59.1   
T 368 39.4 351 40.9 0.5  
IL-1α -889 n % n %   
Genotypes       
CC 220 52.7 209 49.7 0.4  
CT 164 39.3 166 39.5 0.9  
TT 33 7.9 45 10.7 0.2  
Alleles       
C 604 72.4 584 69.5   
T 230 27.6 256 30.5 0.2  
MCP-1 -2518 n % n %   
Genotypes       
AA 238 57.2 250 58.5 0.6  
AG 173 35 154 36 0.7  
GG 39 7.8 23 5.4 0.1  
Alleles       
A 739 74.6 654 76.6   
G 251 25.4 200 23.4 0.3