Table 1 Baseline characteristics of the nested case-control study divided by control group of subjects without atrial fibrillation (AF) and cases with AF. Data shown as percentages for categorical variables and mean ± standard deviation for continuous variables. HDL-cholesterol, Triglycerides, Creatinine, C-reactive protein, and urinary albumin excretion are expressed as median [interquartile range].
| Â | AF Controls (n = 97) | AF Cases (n = 97) | P-value |
|---|---|---|---|
Age, years | 59 ± 1 | 60 ± 1 | Matched |
Male | 56.7% | 56.7% | Matched |
Caucasian | 91.8% | 92.8% | 0.79 |
Body Mass Index | 27.1 ± 0.4 | 27.8 ± 0.4 | 0.24 |
Current smoking | 28.9% | 30.2% | 0.84 |
Ischemic heart disease | 15.8 % | 38.0 % | 0.001 |
Left ventricular hypertrophy | 3.1% | 11.5% | 0.03 |
Systolic blood pressure | 135 ± 2 | 137 ± 2 | 0.47 |
Diastolic blood pressure | 76 ± 1 | 79 ± 1 | 0.03 |
Hypertension | 42.7% | 60.6% | 0.01 |
Diabetes Mellitus | 5.2% | 6.2% | 0.77 |
HDL-cholesterol, mmol/l | 1.24 [1.01–1.56] | 1.18 [0.93–1.47] | 0.29 |
Total cholesterol, mmol/l | 5.9 ± 0.10 | 5.7 ± 0.11 | 0.14 |
LDL cholesterol, mmol/l | 4.0 ± 1.0 | 3.8 ± 1.0 | 0.15 |
Triglycerides, mmol/l | 1.2 [0.9–1.9] | 1.3 [0.9–1.7] | 0.49 |
Creatinine (μmol/L) | 84 [75–95] | 86 [78–105] | 0.07 |
Creatinine clearance (mL/min/1.73 m2) | 90.9 ± 25.7 | 81.2 ± 23.4 | 0.01 |
Moderate renal dysfunction | 14.0% | 40.2% | <0.01 |
C-reactive protein (mg/L) | 1.55 [0.66–2.81] | 2.28 [1.18–4.81] | <0.01 |
Urinary albumin excretion | 11.95 [7.07–21.44] | 17.75 [8.92–45.35] | <0.01 |
Alcohol intake > = 1 drink per day | 24.7 % | 23.7 % | 0.87 |