Risk factor | Status | CAD | CON | Odds ratio | [95% C.I] | pvalue |
---|---|---|---|---|---|---|
Genotype (haplotype) | Twild M wild | 311 | 627 | Reference | - | - |
T1 and M1 genes | Twild Mnull | 280 | 69 | 8.17 | 6.01 – 11.1 | < .001 |
 | Tnull Mwild | 88 | 18 | 9.84 | 5.68 – 17.2 | < .001 |
 | Tnull Mnull | 375 | 48 | 15.7 | 11.2 – 22.2 | < .001 |
Genotype (T1 gene) | T wild | 591 | 696 | Reference | - | - |
 | T null | 463 | 66 | 8.26 | 6.19 – 11.05 | < .001 |
Genotype (M1 gene) | M wild | 399 | 645 | Reference | - | - |
 | M null | 655 | 117 | 9.05 | 7.12 – 11.5 | < .001 |
Smoking | No | 630 | 648 | Reference | - | - |
 | Yes | 424 | 114 | 3.83 | 3.01 – 4.87 | < .001 |
Age | < 40 | 172 | 165 | Reference | - | - |
 | ≥ g40 | 882 | 597 | 1.42 | 1.11 – 1.81 | .004 |
Hypercholesterolemia | No | 369 | 455 | Reference | - | - |
 | Yes | 685 | 307 | 2.71 | 2.27 – 3.34 | < .001 |
Hypertriglyceridemia | No | 438 | 479 | Reference | - | - |
 | Yes | 616 | 283 | 2.38 | 1.97 – 2.89 | < .001 |
DM | No | 462 | 461 | Reference | - | - |
 | Yes | 592 | 301 | 1.96 | 1.62 – 2.37 | < .001 |
FH | No | 764 | 600 | Reference | - | - |
 | Yes | 290 | 162 | 1.40 | 1.13 – 1.75 | .002 |
Gender | F | 412 | 298 | Reference | - | - |
 | M | 642 | 464 | 1.0 | 0.82 – 1.22 | .1 |
Hypertension | No | 89 | 265 | Reference | - | - |
 | Yes | 965 | 497 | 5.77 | 4.41 – 7.59 | < .001 |
Obesity | No | 331 | 417 | Reference | - | - |
 | Yes | 723 | 345 | 2.64 | 2.17 – 3.22 | < .001 |
MI | No | 951 | 707 | Reference | - | - |
 | Yes | 103 | 55 | 1.39 | 0.98 – 1.99 | .067 |