Table 1 Clinical and laboratory features of 47 patients suffering from PCOS and 45 controls included in this genetic study

Age (years)

26.3 ± 5.4

24.6 ± 3.9

NS

Acanthosis nigrans (%)

31.9%

0%

<0.05

Body weight (kg)

72.4 ± 14.5

56.4 ± 9.8

<0.05

BMI (kg/m²)

28.5 ± 6.0

21.7 ± 3.2

<0.05

LH/FSH

2.1 ± 1.0

1.3 ± 0.6

<0.05

Prolactin (ng/ml)

18.6 ± 8.0

12.7 ± 6.3

NS

Testosterone (ng/ml)

1.3 ± 0.5

0.5 ± 0.2

<0.05

SHBG

21.1 ± 8.3

48.1 ± 7.8

<0.05

Fasting glucose (mg/dl)

91.3 ± 18.1

86.3 ± 17.6

NS

IGT (%)

36.2%

6.25%

<0.05

AGT (%)

46.8%

6.25%

<0.05

Fasting insulin (uU/ml)

24.4 ± 17.2

7.9 ± 6.7

<0.05

Glucose/insulin ratio

5.27 ± 3.34

12.13 ± 4.94

<0.05

HOMA_IR

5.21 ± 3.73

1.59 ± 0.65

<0.05