Figure 2
From: N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease
Meta-analysis of NAT2 c.590G>A in PD and control subjects. The confidence interval for each study is given by a horizontal line, and the point estimate is given by a square whose height is inversely proportional to the standard error of the estimate. The summary odds ratio is drawn as a diamond with horizontal limits at the confidence limits and width inversely proportional to its standard error. Allele frequency: Test for heterogeneity χ2 (df 4) = 2.36 (p-value 0.67). The odds ratios are not significantly different between the studies (p = 0.67). The summary odds ratio (Mantel-Haenszel OR= 0.94, 95% CI, 0.79–1.12) is not significantly greater than 1 (p > 0.05). Genotype frequency: Test for heterogeneity χ2 (df 3) = 9.58 (p-value 0.0225). The odds ratios are not significantly different between the studies (p = 0.0225). The summary odds ratio (Mantel-Haenszel OR= 0.94, 95% CI, 0.78–1.43) not significantly different from 1.