Table 2 Genes over-expressed in early passage +21 fibroblasts passing ANOVA at p < .01. Genes on chromosome 21 are in bold.
Affy ID | Gene name | Genbank | Chromosome | Description | Fold change |
|---|---|---|---|---|---|
36040_at | SH3BGR | AI337192 | 21q22.3 | SH3 domain binding glutamic acid-rich protein | 2.52 |
39366_at | PPP1R3C | N36638 | 10q23-q24 | Protein phosphatase 1, regulatory subunit 3C | 1.99 |
31840_at | IDE | M21188 | 10q23-q25 | Insulin-degrading enzyme | 1.98 |
34542_at | GAPDH2 | AJ005371 | 19q13 | glyceraldehyde-3-phosphate dehydrogenase 2 | 1.93 |
37555_at | PWP2 | X95263 | 21q22.3 | PWP2 periodic tryptophan protein homolog | 1.92 |
36088_at | DSCR2 | AJ006291 | 21q22.3 | Leucine-rich protein | 1.74 |
34414_at | KIAA0368 | AB002366 | 9q31.3 | mRNA for KIAA0368 gene | 1.69 |
34367_at | PHGDH | AF006043 | 1p12 | 3-phosphoglycerate dehydrogenase | 1.66 |
35776_at | ITSN1 | AF064243 | 21q22.1-q22.2 | Intersectin 1 (SH3 domain protein) | 1.56 |
32236_at | UBE2G2 | AF032456 | 21q22.3 | Similar to UBC7; ubiquitin conjugating enzyme | 1.50 |
39348_at | HRMT1L1 | X99209 | 21q22.3 | HMT1 hnRNP methyltransferase-like 1 | 1.50 |
38942_r_at | AD024 | W28610 | 2q24.3 | Kinetochore protein Spc25 | 1.45 |
40959_at | PLEKHG3 | AB011171 | 14q23.3 | Pleckstrin homology and rho GEF family | 1.38 |
32738_at | NDUFS2 | AF050640 | 1q23 | NADH-coenzyme Q reductase | 1.36 |