Figure 2
From: On the Wegener granulomatosis associated region on chromosome 6p21.3
Graphical overview of LD analyses with frequent HLA-DPB1 alleles, the rs6531 polymorphism in the RXRB gene and alleles of the significantly WG-associated #1.0.3.7 microsatellite marker. Pair-wise LD evaluated by D' and r 2between markers in the previously found WG associated chromosome 6 region for controls (2A) and patients (2B). Vertical lines with circle, triangle and square represent the relative localisation of each tested marker (HLA-DPB1, RXRB rs6531 and microsatellite marker #1.0.3.7, respectively). D' and r 2 values are indicated by colour coding. Logarithm of odds (LOD) values equal to or exceeding 2 are represented by dashed rectangles, circles or squares. Rectangles are related to LDs between the microsatellite #1.0.3.7 and HLA-DPB1 alleles. Circles represent LD values between HLA-DPB1 and the SNP. Squares show LDs between the microsatellite alleles and rs6531 SNP. The investigated alleles of the microsatellite markers are shown at the left hand side of the figure, whereas the different designations of the HLA-DPB1 alleles are depicted at the right hand side. MS: microsatellite.