Table 3 Association analyses in type 1 diabetes families and case-control sample sets for rheumatoid arthritis, inflammatory bowl disease and multiple sclerosis associated polymorphisms.

IL1RN +2017 T>C rs2419598

0.28

1418 (916/865)

0.23

1.06 [0.96–1.16]

T/T 1.00 [ref] T/C 1.12 [0.99–1.25] C/C 1.03 [0.83–1.28]

n/a

n/a

n/a

n/a

n/a

IL1RA -889 C>T rs1800587

0.30

1431 (925/913)

0.78

1.01 [0.92–1.11]

C/C 1.00 [ref] C/T 1.02 [0.91–1.15] T/T 1.02 [0.83–1.25]

n/a

n/a

n/a

n/a

n/a

CARD15

SNP8 +2023C>T rs2066844

0.03

252 (123/143)

0.22

0.86 [0.68–1.09]

C/C 1.00 [ref] C/T 0.90 [0.70–1.15] T/T 0.22 [0.03–1.66]

n/a

n/a

n/a

n/a

n/a

SNP12 +3641G>C rs2066845

0.01

127 (57/72)

0.19

0.79 [0.56–1.12]

G/G 1.00 [ref] G/C 0.81 [0.57–1.14] C/C -

n/a

n/a

n/a

n/a

n/a

SNP13 +2936insC ss28514842

0.01

143 (73/72)

0.93

1.01 [0.73–1.40]

1/1 1.00 [ref] 1/2 1.00 [0.72–1.38] 2/2 2.99 [0.19–48.22]

n/a

n/a

n/a

n/a

n/a

IGR2198 G>C rs11739135

0.40

1511 (988/1008)

0.65

0.98 [0.90–1.07]

G/G 1.00 [ref] G/C 0.95 [0.84–1.07] C/C 0.98 [0.82–1.17]

n/a

n/a

n/a

n/a

n/a

SLC22A4 G>A rs3792876

n/a

n/a

n/a

n/a

n/a

0.08

3303/3558

0.93

0.99 [0.87–1.14]

C/C 1.0 [ref] C/T 1.01 [0.87–1.16] T/T 0.83 [0.40–1.70]

SLC22A4 C>T rs2073838

n/a

n/a

n/a

n/a

n/a

0.08

3290/3549

0.79

0.98 [0.86–1.12]

G/G 1.00 [ref] G/A 1.00 [0.87–1.15] A/A 0.74 [0.36–1.52]

LAG3 G>A rs870849

n/a

n/a

n/a

n/a

n/a

0.36

3860/4297

0.90

1.00 [0.93–1.06]

G/G 1.00 [ref] G/A 1.00 [0.91–1.10] A/A 0.99 [0.86–1.14]