Published SNP | Set 1 families | Cases and controls | ||||||||
---|---|---|---|---|---|---|---|---|---|---|

MAF | N parent-child trios (T/NT) |
P_{TDT}
| Allelic RR [95% CI] | Genotype RR [95% CI] | MAF | N cases/controls |
P_{1df}
| Allelic OR [95% CI] | Genotype OR [95% CI] | |

FCRL3 A>G rs7528684
| 0.46 | 901 (641/571) | 0.04 | 0.89 [0.80–1.00] | A/A 1.00 [ref] A/G 0.88 [0.75–1.04] G/G 0.79 [0.63–1.00] | 0.45 | 1896/2020 | 0.97 | 1.00 [0.91–1.10] | A/A 1.00 [ref] A/G 1.02 [0.87–1.18] G/G 0.99 [0.82–1.20] |

CFH A>G rs1061170
| 0.38 | 823 (541/517) | 0.46 | 0.96 [0.85–1.08] | A/A 1.00 [ref] A/G 1.00 [0.85–1.17] G/G 0.88 [0.68–1.14] | 0.38 | 3149/3485 | 0.87 | 0.99 [0.92–1.07] | A/A 1.00 [ref] A/G 1.07 [0.96–1.19] G/G 0.94 [0.81–1.10] |

SLC9A3R1 G>A rs734232
| 0.45 | 965 (644/642) | 0.96 | 1.00 [0.90–1.12] | G/G 1.00 [ref] G/A 1.03 [0.88–1.21] A/A 1.00 [0.80–1.25] | 0.45 | 1578/1736 | 0.34 | 1.05 [0.95–1.17] | G/G 1.00 [ref] G/A 0.92 [0.78–1.10] A/A 1.14 [0.92–1.41] |

PADI4 C>T rs2240340
| 0.41 | 942 (610/655) | 0.21 | 1.07 [0.96–1.20] | T/T 1.00 [ref] C/T 1.07 [0.92–1.25] C/C 1.15 [0.92–1.44] | 0.42 | 1573/1732 | 0.87 | 1.01 [0.91–1.12] | T/T 1.00 [ref] C/T 1.09 [0.92–1.29] C/C 0.99 [0.80–1.23] |

RUNX1 C>G rs2268277
| 0.34 | 896 (578/565) | 0.70 | 1.02 [0.91–1.15] | T/T 1.00 [ref] T/C 0.96 [0.83–1.11] C/C 1.12 [0.87–1.43] | 0.36 | 1586/1725 | 0.21 | 0.93 [0.84–1.04] | T/T 1.00 [ref] T/C 0.90 [0.76–1.05] C/C 0.90 [0.71–1.14] |

SPINK5
| ||||||||||

+316 A>C ss28514851 | 0.04 | 178 (89/91) | 0.88 | 0.98 [0.73–1.31] | A/A 1.00 [ref] A/C 0.98 [0.73–1.31] C/C 0.98 [0.10–9.55] | 0.03 | 1540/1678 | 0.40 | 0.88 [0.66–1.18] | A/A 1.00 [ref] A/C 0.88 [0.65–1.19] C/C 0.82 [0.14–4.71] |

+1103 T>C rs2303064 | 0.48 | 915 (583/602) | 0.58 | 0.97 [0.86–1.09] | T/T 1.00 [ref] T/C 0.99 [0.84–1.17] C/C 0.94 [0.74–1.18] | 0.47 | 1527/1665 | 0.30 | 0.95 [0.85–1.05] | T/T 1.00 [ref] T/C 0.96 [0.80–1.14] C/C 0.89 [0.72–1.10] |

+1156 G>A rs2303063 | 0.10 | 357 (196/213) | 0.40 | 0.92 [0.76–1.12] | G/G 1.00 [ref] G/A 0.93 [0.75–1.15] A/A 0.81 [0.42–1.57] | 0.11 | 1530/1507 | 0.03 2 df | 0.87 [0.73–1.04] | G/G 1.00 [ref] G/A 0.79 [0.64–0.96] A/A 1.48 [0.72–3.03] |

+1258 C>T rs2303067 | 0.48 | 947 (617/622) | 0.89 | 0.99 [0.89–1.11] | C/C 1.00 [ref] C/T 1.03 [0.87–1.22] T/T 0.98 [0.79–1.23] | 0.47 | 1534/1641 | 0.36 | 0.95 [0.85–1.06] | C/C 1.00 [ref] C/T 0.98 [0.82–1.17] T/T 0.90 [0.73–1.12] |

+2475 C>A rs2303070 | 0.07 | 317 (150/186) | 0.05 | 0.81 [0.65–1.00] | C/C 1.00 [ref] C/A 0.85 [0.68–1.06] A/A 0.15 [0.02–1.13] | 0.08 | 1479/1513 | 0.06 2 df | 0.91 [0.73–1.12] | C/C 1.00 [ref] C/A 0.82 [0.66–1.04] A/A 2.51 [0.81–7.79] |

+2915 A>G ss28514856 | 0.04 | 184 (92/105) | 0.35 | 0.88 [0.66–1.16] | A/A 1.00 [ref] A/G 0.87 [0.65–1.17] G/G 0.82 [0.22–3.03] | 0.03 | 1547/1685 | 0.91 | 0.98 [0.72–1.33] | A/A 1.00 [ref] A/G 0.98 [0.72–1.33] G/G - |