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Table 4 Results of pair-wise LD analyses

From: A detailed Hapmap of the Sitosterolemia locus spanning 69 kb; differences between Caucasians and African-Americans

Population

M1

M2

ChiSq

Pval

Δ2

D'

Caucasian

INT1-21

INT1-7

20.01

1E-05

0.545

0.866

 

5'UTR-19

INT1-7

9.61

0.002

0.256

0.594

 

Q604E

INT1-7

7.14

0.008

0.239

0.489

 

T400K

A632V

6.13

0.013

0.125

1.000

 

5'UTR-19

T400K

5.84

0.016

0.153

1.000

 

Q604E

D19H

5.02

0.025

0.174

1.000

 

INT1-7

T400K

4.94

0.026

0.111

1.000

 

R50C

D19H

4.79

0.029

0.234

0.484

 

INT1-21

T400K

4.45

0.035

0.153

1.000

 

E238L

INT10-50

4.42

0.036

0.238

1.000

 

INT1-7

C54Y

4.41

0.036

0.138

0.739

 

5'UTR-19

C54Y

4.24

0.040

0.134

0.619

 

T400K

INT10-50

3.92

0.048

0.040

1.000

 

5'UTR-19

A565A

3.86

0.049

0.127

1.000

 

Q604E

INT1-21

3.66

0.056

0.128

0.420

 

INT10-50

A632V

3.29

0.070

0.132

0.641

 

5'UTR-19

INT1-21

2.86

0.091

0.071

0.267

 

C54Y

T400K

2.74

0.098

0.082

0.433

African-American

5'UTR-19

T400K

11.01

9E-04

0.080

1.000

 

INT1-7

A565A

8.09

0.004

0.085

0.587

 

R50C

D19H

6.96

0.008

0.205

1.000

 

T400K

A565A

6.56

0.010

0.088

0.557

 

Q604E

INT1-21

5.82

0.016

0.119

0.505

 

5'UTR-19

A565A

5.10

0.024

0.059

0.460

 

C54Y

A565A

3.93

0.047

0.053

0.270

 

5'UTR-19

C54Y

3.49

0.062

0.047

0.481

 

R50C

INT1-7

3.05

0.081

0.044

1.000

 

INT1-7

A632V

3.05

0.081

0.044

1.000

 

Q604E

D19H

3.01

0.083

0.038

1.000

  1. M1 = 1st marker in pair of SNPs, M2 = 2nd marker in pair of SNPs, ChiSq = Value of chi-square test of association, Pval = Two-sided P-value corresponding to chi-square value in ChiSq column assuming 1 degree of freedom.
  2. Δ2 = Estimated value of Delta-squared measure of LD.
  3. D' = Estimated value of Lewontin's [37] measure of LD.