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Table 2 Number of up- or down-regulated genes in the discordant twins with MS compared to their healthy siblings.

From: Gene expression profiles in Finnish twins with multiple sclerosis

 

Number of twin pairs

 

1/8*

2/8**

3/8

Up-regulated

194

25

6

Down-regulated

111

15

0

Total no of genes with change

305

38

6

  1. Genes with at least two-fold change are included.
  2. The proportion of up-regulated genes was significantly higher compared to the proportion of down-regulated genes within twin pair groups *p = 0.023; **p = 0.01 in X-2 test.