From: Association between a variation in the phosphodiesterase 4D gene and bone mineral density
 | Australian Twin Replication | International Replication | |
---|---|---|---|
Trait | Females (N = 590) | Males (N = 141) | Females (N = 805) |
Age (years) | 40/52/61 | 47/54/64 | 52/59/67 |
Twin status | Â | Â | Â |
   Singletons | 42% (246) | 48% (67) | N/A |
   Dizygotic pairs | 58% (72) | 52% (37) | N/A |
Smoking status | Â | Â | Â |
   Never | 63% (368) | 55% (78) | 52% (317) |
   Former | 24% (141) | 30% (42) | 26% (157) |
   Current | 13% (77) | 15% (21) | 22% (130) |
Weight (kg) | 58/64/74 | 73/81/91 | 55/60/69 |
BMI | 22/25/28 | 25/27/29 | 22/24/27 |
BMD spine (g/cm2) | 0.89/0.99/1.09 | 0.92/1.03/1.13 | 0.71/0.80/0.94 |
Adjusted BMD spine (g/cm2) | 0.89/0.99/1.06 | 0.93/1.02/1.12 | 0.74/0.81/0.92 |
BMD hip (g/cm2) | 0.85/0.93/1.02 | 0.96/1.05/1.14 | 0.68/0.77/0.87 |
BMD femoral neck (g/cm2) | 0.71/0.79/0.88 | 0.78/0.86/0.95 | 0.57/0.65/0.73 |
BMD forearm (g/cm2) | 0.51/0.55/0.59 | 0.61/0.66/0.69 | N/A |