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Table 3 Characteristics of complete genotyped replication samples.

From: Association between a variation in the phosphodiesterase 4D gene and bone mineral density

 

Australian Twin Replication

International Replication

Trait

Females (N = 590)

Males (N = 141)

Females (N = 805)

Age (years)

40/52/61

47/54/64

52/59/67

Twin status

   

   Singletons

42% (246)

48% (67)

N/A

   Dizygotic pairs

58% (72)

52% (37)

N/A

Smoking status

   

   Never

63% (368)

55% (78)

52% (317)

   Former

24% (141)

30% (42)

26% (157)

   Current

13% (77)

15% (21)

22% (130)

Weight (kg)

58/64/74

73/81/91

55/60/69

BMI

22/25/28

25/27/29

22/24/27

BMD spine (g/cm2)

0.89/0.99/1.09

0.92/1.03/1.13

0.71/0.80/0.94

Adjusted BMD spine (g/cm2)

0.89/0.99/1.06

0.93/1.02/1.12

0.74/0.81/0.92

BMD hip (g/cm2)

0.85/0.93/1.02

0.96/1.05/1.14

0.68/0.77/0.87

BMD femoral neck (g/cm2)

0.71/0.79/0.88

0.78/0.86/0.95

0.57/0.65/0.73

BMD forearm (g/cm2)

0.51/0.55/0.59

0.61/0.66/0.69

N/A

  1. Categorical variables are reported as frequency percent (count). Quantitative variables are reported as 1st quartile / median / 3rd quartile.