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Table 4 Urinary potassium excretion and relation to plasma renin and aldosterone levels

From: Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

  Carriers of the ENaC variants Non-carriers P-values
  βENaC i12-17CT (n = 14) βENaC G589S (n = 7) γENaC V546I (n = 5) All (n = 26) (n = 236) All variants versus non-carriers
dU-K (mmol) 86 (68–112) 85 (66–120) 80 (70–96) 83 (68–102) 79 (65–94) 0.23
dU-K/PRA upright 54 (31–122) 57 (38–180) 97 (43–274) 56 (35–129) 38 (23–84) 0.034
dU-K/PRA mean 67 (37–168) 77 (55–252) 107 (59–321) 74 (46–170) 51 (31–118) 0.048
dU-K/Aldo upright 0.15 (0.06–0.25) 0.10 (0.07–0.15) 0.08 (0.06–0.25) 0.10 (0.07–0.21) 0.08 (0.06–0.14) 0.108
  1. Data is given as median (interquartile range). dU-K, daily urinary potassium excretion; PRA, plasma renin activity (μg/L/h); Aldo, serum aldosterone concentration (pmol/L); PRA mean, average of supine and upright PRA.