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Figure 5 | BMC Medical Genetics

Figure 5

From: Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

Figure 5

Channel activity of βENaC G589S and γENaC V546I variants in vitro. Comparison of channel activity of hENaC wild-type, and the βhENaC G589S and γhENaC V546I variants, when expressed in Xenopus oocytes. ENaC activity was measured as amiloride-sensitive Na+ current. Absolute currents were 5.09 ± 0.98 and 6.75 ± 1.23 μA for ENaC wt in the two series of experiments (number of oocytes given in parentheses).

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