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Table 5 Haplotypes for 8, 4, and 3 Markers Observed in the African American Population

From: Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans

Variants No Haplotype Case Freq Control Freq ChiSq P value Simulated p value Global p
1,4,6,5,2,11,8,P  
  1 CAGCGIGD 0.531 0.511 0.326 0.5683 1 0.01
  2 TTTCGDTD 0.103 0.145 3.336 0.0678 0.465  
  3 CTGCAIGD 0.112 0.124 0.247 0.6193 1  
  4 CAGCGIGI 0.108 0.064 4.676 0.0306 0.239  
  5 CAGTGIGD 0.072 0.046 2.389 0.1222 0.693  
  6 TTGCGDGD 0.031 0.067 5.873 0.0154 0.131  
  7 CTGCGIGD 0.026 0.024 0.014 0.9057 1  
1,4,11,P         
  1 CAID 0.622 0.565 3.197 0.0738 0.3053 0.01
  2 TTDD 0.138 0.209 9.084 0.0026 0.0094  
  3 CTID 0.143 0.151 0.134 0.714 0.9995  
  4 CAII 0.088 0.059 2.735 0.098 0.3809  
1,4,11         
  1 CAI 0.71 0.625 7.96 0.0048 0.02 0.01
  2 TTD 0.138 0.209 9.085 0.0026 0.011  
  3 CTI 0.145 0.152 0.091 0.763 1  
  1. Haplotypes observed at over 1% frequency for all 8 variants, the 4 variants typed in additional individuals, and the three variants that showed an association with T2DM. Simulated p values are based on 10,000 simulations in HaploView 3.2; global p values are based on simulations conducted in Phase 2.1.1.